Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3509099 | 1.00 | CFTR (0.51) | CFTRBRD4PLGPLAUSLC6A2 | |
| SCHEMBL917196 | 0.90 | BRD4 (0.51) | CFTRBRD4SLC2A1POLBNPC1 | |
| Ethoxycarbonyl Group SCHEMBL27751175 | 0.89 | CFTR (0.43) | CFTRBRD4PLGPLAUSLC6A2 | |
| SCHEMBL31035977 | 0.84 | SLC6A2 (0.47) | PLGPLAUSLC6A2NPC1HSP90AA1 | |
| SCHEMBL29263648 | 0.84 | SLC6A2 (0.47) | PLGPLAUSLC6A2NPC1HSP90AA1 | |
| SCHEMBL2263749 | 0.80 | NPC1 (0.64) | PLGPLAUNPC1HSP90AA1ALDH1A1 | |
| SCHEMBL938567 | 0.79 | GLS (0.62) | CFTRPOLBNPC1L3MBTL1CYP1A2 | |
| SCHEMBL3506156 | 0.79 | PLG (0.45) | PLGPLAUSLC6A2NPC1HSP90AA1 | |
| SCHEMBL29377752 | 0.79 | GLS (0.62) | CFTRPOLBNPC1L3MBTL1CYP1A2 | |
| SCHEMBL3506073 | 0.79 | SERPINE1 (0.45) | PLGPLAUNPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151487-A2 | SMALL-MOLECULE INHIBITORS OF ADAR1 | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-07-17 | — | — | WO | disclosed |