Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | PLAU | P00749 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086252 | 1.00 | HTR6 (0.54) | HTR6PLAUPLGPRKCIEGFR | |
| SCHEMBL6355917 | 0.85 | PRKCI (0.46) | HTR6PLAUPLGPRKCIEGFR | |
| SCHEMBL2769024 | 0.84 | HTR6 (0.66) | HTR6PLAUPLGPRKCIEGFR | |
| SCHEMBL30241534 | 0.84 | HTR6 (0.66) | HTR6PLAUPLGPRKCIEGFR | |
| SCHEMBL9198838 | 0.83 | HTR2A (0.51) | HTR6PLAUPLGEGFR | |
| SCHEMBL7084091 | 0.82 | PLAU (0.50) | HTR6PLAUPLGEGFRKDM4C | |
| SCHEMBL31661458 | 0.82 | PLAU (0.50) | HTR6PLAUPLGEGFRKDM4C | |
| SCHEMBL8845761 | 0.81 | HTR6 (0.49) | HTR6PLAUPLGMAOBKDM4C | |
| SCHEMBL171614 | 0.81 | SLC6A2 (0.50) | HTR6PLAUPLGMAOB | |
| SCHEMBL11959087 | 0.81 | HTR2A (0.51) | HTR6PLAUPLGMAOBKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151487-A2 | SMALL-MOLECULE INHIBITORS OF ADAR1 | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-07-17 | — | — | WO | disclosed |