SCHEMBL31661863

SCHEMBL31661863

N=C(N)c1ccccc1-c1ncc[nH]1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1A1 P48729 1/20 0.71
TYRO3 Q06418 1/20 0.71
DYRK1B Q9Y463 1/20 0.71
NISCH Q9Y2I1 2/20 0.46
MTOR P42345 1/20 0.46
ADK P55263 1/20 0.46
IDO1 P14902 1/20 0.42
HCRTR1 O43613 2/20 0.40
HCRTR2 O43614 2/20 0.40
PARP1 P09874 1/20 0.40
ADRA1A P35348 1/20 0.39
NUDT1 P36639 1/20 0.38
CASP6 P55212 1/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
ADRB3 P13945 1/20 0.37
ADRA2A P08913 1/20 0.36
KDM4E B2RXH2 1/20 0.36
KLK1 P06870 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4606701 1.00 CSNK1A1 (0.71) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL9234252 0.83 CSNK1A1 (0.71) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL6825869 0.83 CSNK1A1 (1.00) CSNK1A1TYRO3DYRK1BNISCHMTOR
Water SCHEMBL30473073 0.82 CSNK1A1 (0.97) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL10714674 0.79 CSNK1A1 (0.76) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL30965100 0.78 CSNK1A1 (0.73) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL297622 0.78 CSNK1A1 (0.73) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL9287236 0.78 NISCH (0.64) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL15478263 0.77 CSNK1A1 (0.71) CSNK1A1TYRO3DYRK1BNISCHMTOR
SCHEMBL11566235 0.77 CSNK1A1 (0.71) CSNK1A1TYRO3DYRK1BNISCHMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151705-A1 NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY VRISE THERAPEUTICS, INC. (US) 2025-07-17 WO disclosed