Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.73 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.73 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | ADK | P55263 | 1/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965100 | 1.00 | CSNK1A1 (0.73) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL5854599 | 0.98 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| SCHEMBL10714674 | 0.88 | CSNK1A1 (0.76) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| SCHEMBL28348460 | 0.87 | CSNK1A1 (0.60) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| SCHEMBL6005082 | 0.85 | CSNK1A1 (0.68) | CSNK1A1TYRO3DYRK1BKDM4EMTOR | |
| SCHEMBL6825869 | 0.85 | CSNK1A1 (1.00) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| SCHEMBL15478263 | 0.85 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BKDM4EMTOR | |
| SCHEMBL11566235 | 0.85 | CSNK1A1 (0.71) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| SCHEMBL27401060 | 0.84 | CSNK1A1 (0.57) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A | |
| Water SCHEMBL30473073 | 0.83 | CSNK1A1 (0.97) | CSNK1A1TYRO3DYRK1BKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863894-B | Tanshinone II A derivative and preparation method and application thereof | UNIV GUANGDONG PHARM | 2012-07-18 | — | — | CN | claimed |
| CN-101863894-A | Tanshinone II A derivative and preparation method and application thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY | 2010-10-20 | — | — | CN | claimed |
| CN-101735217-A | Application of imidazole [4,5-f][1,10] phenanthroline and derivative thereof to preparation of antineoplastic drug | UNIV GUANGDONG PHARM | 2010-06-16 | — | — | CN | claimed |
| EP-3693434-B1 | ADHESIVE COMPOSITION FOR SEMICONDUCTOR CIRCUIT CONNECTION AND ADHESIVE FILM INCLUDING THE SAME | LG CHEMICAL LTD (KR) | 2025-10-08 | — | — | EP | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-04 | — | — | US | disclosed |
| US-11834415-B2 | Adhesive composition for semiconductor circuit connection and adhesive film including the same | LG CHEM, LTD. (KR) | 2023-12-05 | — | — | US | disclosed |
| US-11667644-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-06 | — | — | US | disclosed |
| CN-114262443-B | Lanthanide metal organic framework material, and synthesis method and application thereof | 中国科学院福建物质结构研究所 | 2022-10-14 | — | — | CN | disclosed |
| CN-114262443-A | Lanthanide metal organic framework material, and synthesis method and application thereof | 中国科学院福建物质结构研究所 | 2022-04-01 | — | — | CN | disclosed |
| US-RE48841-E1 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-07 | — | — | US | disclosed |
| CN-101139346-A | Benzimidazole-derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-12 | — | — | CN | disclosed |
| US-20050038067-A1 | Asymmetric benzimidazoles and related compounds as potassium channel modulators | ICAGEN, INC. (US) | 2005-02-17 | — | — | US | disclosed |
| WO-2005002503-A2 | ASYMMETRIC BENZIMIDAZOLES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-0169164-B1 | IMIDAZOLONECARBONYLARYLIMIDAZOLES; METHOD OF MANUFACTURE, METHOD OF USE AND COMPOSITIONS USEFUL THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-01-31 | — | — | EP | disclosed |
| US-4874747-A | DERMATOLOGY | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1989-10-17 | — | — | US | disclosed |
| US-4777250-A | LOW MOLECULAR WEIGHT; STABLE | NORTHWESTERN UNIVERSITY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4709043-A | Process for the preparation of imidazolonecarbonylarylimidazoles | SCHERING A.G. (DE) | 1987-11-24 | — | — | US | disclosed |
| EP-0169164-A1 | Imidazolonecarbonylarylimidazoles; method of manufacture, method of use and compositions useful thereof | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4556665-A | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones | SCHERING A.G. (DE) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, OXTR | CSNK1A1 3832/4885TYRO3 2113/4885DYRK1B 2529/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | CSNK1A1 3832/4885TYRO3 2113/4885DYRK1B 2529/4885 |
| US-20050038067-A1 | Asymmetric benzimidazoles and related compounds as potassium channel modulators | KCNJ2, KCNJ1, KCNJ11 | CSNK1A1 2237/4885TYRO3 3998/4885DYRK1B 779/4885 |
| US-11834415-B2 | Adhesive composition for semiconductor circuit connection and adhesive film including the same | ASH2L, CDH1, AS3MT | CSNK1A1 4026/4885TYRO3 1113/4885DYRK1B 2356/4885 |
| US-11667644-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | CSNK1A1 3832/4885TYRO3 2113/4885DYRK1B 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.