SCHEMBL31661970

SCHEMBL31661970

C=CC(=O)NC(C)c1ccc(F)c(OC)c1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACACB O00763 2/20 0.46
ROCK2 O75116 1/20 0.45
PRKG1 Q13976 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
BACE1 P56817 2/20 0.40
ALOX5 P09917 1/20 0.39
CYP2C19 P33261 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30032771 0.87 HPGD (0.58) ACACBHPGDSMN1; SMN2CA1CA2
SCHEMBL31661855 0.82 ACACB (0.46) ACACBSMN1; SMN2CYP2C19
SCHEMBL19889077 0.80 PSMB11 (0.52) ACACBHPGD
SCHEMBL31662030 0.80 CNR1 (0.48) ACACBROCK2PRKG1HPGDSMN1; SMN2
SCHEMBL23122086 0.78 HPGD (0.48) ROCK2PRKG1HPGDSMN1; SMN2
SCHEMBL23122084 0.78 HPGD (0.48) ROCK2PRKG1HPGDSMN1; SMN2
SCHEMBL29757911 0.78 HPGD (0.48) ROCK2PRKG1HPGDSMN1; SMN2
SCHEMBL30230833 0.77 ACACB (0.63) ACACBALOX5CA1CA2ACHE
SCHEMBL18794453 0.75 ROCK2 (0.43) ROCK2PRKG1HPGDSMN1; SMN2CA1
SCHEMBL4596488 0.75 TSHR (0.38) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149629-A1 NOVEL CARBOXAMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-17 WO disclosed