⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662017 | 0.75 | MAPK1 (0.30) | — | |
| SCHEMBL31662081 | 0.67 | KMT2A (0.37) | — | |
| SCHEMBL31662089 | 0.65 | LMNA (0.31) | — | |
| SCHEMBL29508069 | 0.59 | MERTK (0.30) | — | |
| SCHEMBL28734801 | 0.59 | MERTK (0.30) | — | |
| SCHEMBL28734989 | 0.58 | — | — | |
| SCHEMBL29508820 | 0.58 | — | — | |
| SCHEMBL28734722 | 0.57 | HTT (0.38) | — | |
| SCHEMBL28734862 | 0.57 | HTT (0.38) | — | |
| SCHEMBL29508868 | 0.57 | HTT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |