Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 4/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662019 | 1.00 | IRAK4 (0.36) | IRAK4SCN9ACHRM1JAK1JAK3 | |
| SCHEMBL31662279 | 0.89 | IRAK4 (0.37) | IRAK4SCN9ACHRM1JAK1JAK3 | |
| SCHEMBL31662162 | 0.89 | IRAK4 (0.37) | IRAK4SCN9ACHRM1JAK1JAK3 | |
| SCHEMBL31662135 | 0.89 | IRAK4 (0.37) | IRAK4SCN9ACHRM1JAK1JAK3 | |
| SCHEMBL31662165 | 0.87 | IRAK4 (0.37) | IRAK4SCN9AJAK1JAK3SYK | |
| SCHEMBL31661902 | 0.86 | SCN9A (0.35) | IRAK4SCN9ACHRM1SYKRET | |
| SCHEMBL31661879 | 0.86 | SCN9A (0.35) | IRAK4SCN9ACHRM1SYKRET | |
| SCHEMBL31662005 | 0.86 | SCN9A (0.35) | IRAK4SCN9ACHRM1SYKRET | |
| SCHEMBL31662113 | 0.84 | SCN9A (0.39) | IRAK4SCN9ASYKHAO1HTR3A | |
| SCHEMBL31661929 | 0.83 | IRAK4 (0.37) | IRAK4SCN9AJAK1JAK3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |