⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662361 | 0.90 | — | — | |
| SCHEMBL31662039 | 0.83 | LMNA (0.31) | — | |
| SCHEMBL31661979 | 0.76 | — | — | |
| SCHEMBL31662215 | 0.72 | — | — | |
| SCHEMBL31662014 | 0.71 | KRAS (0.42) | — | |
| SCHEMBL31662348 | 0.70 | — | — | |
| SCHEMBL31527485 | 0.70 | — | — | |
| SCHEMBL31526917 | 0.65 | — | — | |
| SCHEMBL31196812 | 0.60 | — | — | |
| SCHEMBL25081023 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |