Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662206 | 0.92 | KRAS (0.60) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31348565 | 0.87 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31662044 | 0.87 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31662268 | 0.87 | KRAS (0.50) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30702938 | 0.86 | KRAS (0.58) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30702897 | 0.86 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31348400 | 0.86 | KRAS (0.60) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30810145 | 0.83 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27243469 | 0.83 | KRAS (0.57) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31662374 | 0.83 | KRAS (0.46) | KRASMAPK3MAPK1RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |