Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768328 | 0.86 | HASPIN (0.46) | HASPINCLK1KDM4ELMNAHTT | |
| SCHEMBL31662056 | 0.79 | KDM4E (0.39) | HASPINKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL31194906 | 0.77 | CLK1 (0.42) | CLK1KDM4ELMNAHTTPOLB | |
| SCHEMBL3816236 | 0.77 | KDM4E (0.59) | KDM4ELMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24175001 | 0.77 | CLK1 (0.42) | CLK1KDM4ELMNAHTTPOLB | |
| SCHEMBL31235431 | 0.76 | HASPIN (0.42) | HASPINKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL26157498 | 0.76 | DCPS (0.55) | CLK1KDM4EHTTPOLBRAD52 | |
| SCHEMBL30901027 | 0.73 | HTT (0.51) | CLK1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL31662312 | 0.70 | CLK1 (0.38) | CLK1KDM4ELMNAHTTPOLB | |
| SCHEMBL15565731 | 0.69 | HASPIN (0.53) | HASPINCLK1KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151594-A1 | FUSED AZINES AS RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |