Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30286434 | 0.96 | KMT2A (0.36) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL21988942 | 0.96 | KMT2A (0.36) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL22045916 | 0.84 | KMT2A (0.39) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL21989101 | 0.84 | DGAT1 (0.34) | DGAT1NPC1KMOMAPTALDH1A1 | |
| SCHEMBL21988831 | 0.84 | HSD17B10 (0.37) | TSHRHSD17B10DGAT1NPC1KMO | |
| SCHEMBL25807918 | 0.81 | KMT2A (0.35) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL31662536 | 0.81 | KMT2A (0.48) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL15917685 | 0.80 | DGAT1 (0.35) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL20604807 | 0.80 | HSD17B10 (0.34) | KMT2AMEN1KDM4EGAATSHR | |
| SCHEMBL21796612 | 0.80 | DGAT1 (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |