Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662657 | 1.00 | CA12 (0.39) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL31662329 | 1.00 | CA12 (0.39) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL31076408 | 0.83 | CA12 (0.41) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL31662627 | 0.83 | CA12 (0.41) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL14803666 | 0.81 | CYP2D6 (0.46) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL2566829 | 0.80 | CA12 (0.43) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL23210111 | 0.80 | CA12 (0.44) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL31662565 | 0.79 | CA12 (0.40) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL22633334 | 0.78 | CYP2D6 (0.43) | CA12CA1CA9CYP2D6CYP1A2 | |
| SCHEMBL22633332 | 0.78 | CYP2D6 (0.43) | CA12CA1CA9CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |