Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12097863 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL15574085 | 0.93 | STAT3 (0.39) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL5722589 | 0.90 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL4347000 | 0.88 | ALDH1A1 (0.42) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL10171748 | 0.88 | ALDH1A1 (0.42) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL2222219 | 0.88 | ALDH1A1 (0.42) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL11772941 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL11770124 | 0.87 | ALDH1A1 (0.40) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL1846086 | 0.86 | CYP2D6 (0.38) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 | |
| SCHEMBL1192284 | 0.85 | SLC12A2 (0.40) | ALDH1A1CYP2D6CYP3A4TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |