Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12560150 | 1.00 | L3MBTL1 (0.45) | L3MBTL1NPC1HSP90AA1CYP2A6EGFR | |
| Charcoal, Activated SCHEMBL11434519 | 0.98 | L3MBTL1 (0.43) | L3MBTL1NPC1HSP90AA1CYP2A6EGFR | |
| SCHEMBL6371727 | 0.75 | EGFR (0.40) | L3MBTL1NPC1HSP90AA1EGFRKDM4E | |
| SCHEMBL12559949 | 0.74 | EGFR (0.41) | L3MBTL1NPC1HSP90AA1EGFRKDM4E | |
| SCHEMBL2210491 | 0.74 | EGFR (0.41) | L3MBTL1NPC1HSP90AA1EGFRKDM4E | |
| SCHEMBL29427603 | 0.74 | PI4KA (0.52) | HSP90AA1EGFRKDM4EMAPTLMNA | |
| SCHEMBL1065478 | 0.74 | PDE4A (0.52) | L3MBTL1NPC1HSP90AA1EGFRKDM4E | |
| SCHEMBL2041433 | 0.74 | PI4KA (0.52) | HSP90AA1EGFRKDM4EMAPTLMNA | |
| SCHEMBL6837820 | 0.74 | EGFR (0.41) | L3MBTL1NPC1HSP90AA1EGFRKDM4E | |
| SCHEMBL30880053 | 0.74 | EGFR (0.41) | L3MBTL1NPC1HSP90AA1EGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |