SCHEMBL31662995

SCHEMBL31662995

c1cc2ccc(CNc3cnc4ccc(N5CCCC5)nc4n3)cc2[nH]1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MET P08581 1/20 0.43
PARP1 P09874 2/20 0.39
PARP2 Q9UGN5 1/20 0.39
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
ABL1 P00519 1/20 0.38
MAPK1 P28482 2/20 0.38
KIT P10721 1/20 0.38
CCNT1 O60563 1/20 0.37
CDK9 P50750 1/20 0.37
P2RX3 P56373 1/20 0.36
P2RX2 Q9UBL9 1/20 0.36
MAP4K4 O95819 1/20 0.35
F2 P00734 1/20 0.35
MAPK8 P45983 1/20 0.34
BACE1 P56817 1/20 0.34
METTL3 Q86U44 1/20 0.34
METTL14 Q9HCE5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663058 0.99 MET (0.42) METPARP1PARP2PDE4APDE4B
SCHEMBL31663287 0.98 MET (0.43) METPARP1PARP2PDE4APDE4B
SCHEMBL31663227 0.92 MET (0.42) METPARP1PARP2PDE4APDE4B
SCHEMBL31663126 0.91 MET (0.53) METPARP1PARP2CCNT1CDK9
SCHEMBL31663367 0.91 PIK3CA (0.43) METPARP1PARP2ABL1MAPK1
SCHEMBL31663005 0.90 MET (0.41) METPARP1PARP2ABL1MAPK1
SCHEMBL31663117 0.88 MET (0.38) METPARP1PARP2ABL1MAPK1
SCHEMBL31662872 0.88 MET (0.39) METPARP1PARP2ABL1MAPK1
SCHEMBL31663073 0.88 MET (0.41) METPARP1PARP2PDE4DABL1
SCHEMBL31663044 0.88 MET (0.39) METPARP1PARP2PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149622-A1 WNK1 INHIBITORS DANIA THERAPEUTICS APS (DK) 2025-07-17 WO claimed
WO-2025149622-A1 WNK1 INHIBITORS DANIA THERAPEUTICS APS (DK) 2025-07-17 WO disclosed