Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.57 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1653114 | 0.86 | KDM4E (0.62) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL408202 | 0.85 | GPR119 (0.63) | GPR119CCNA2CDK2KDM4EPKM | |
| SCHEMBL31663119 | 0.83 | GPR119 (0.50) | GPR119PTPN2PTPN1PTPN6STS | |
| SCHEMBL5762340 | 0.83 | GPR119 (0.58) | GPR119CCNA2CDK2KDM4EPKM | |
| SCHEMBL13391294 | 0.82 | GPR119 (0.59) | GPR119CCNA2CDK2KDM4EPKM | |
| SCHEMBL31663186 | 0.82 | STS (0.50) | GPR119KDM4EPKMPTPN2PTPN1 | |
| SCHEMBL3296733 | 0.81 | GPR119 (0.58) | GPR119CCNA2CDK2KDM4EPKM | |
| SCHEMBL3296734 | 0.81 | GPR119 (0.58) | GPR119CCNA2CDK2KDM4EPKM | |
| SCHEMBL25217450 | 0.81 | GPR119 (0.57) | GPR119CCNA2CDK2GAAPTPN2 | |
| SCHEMBL31663026 | 0.80 | POLB (0.52) | GPR119KDM4EPKMPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |