Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663320 | 0.80 | DHODH (0.36) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31663319 | 0.77 | ALDH1A1 (0.37) | CYP1A2CYP3A4ADORA1GAAKMT2A | |
| SCHEMBL31663140 | 0.73 | KDM4E (0.40) | CYP1A2ADORA1GAAKMT2AADORA2A | |
| SCHEMBL20605048 | 0.72 | HTT (0.41) | CYP1A2CYP3A4CYP2D6GAAKMT2A | |
| SCHEMBL21087260 | 0.70 | NPSR1 (0.43) | CYP1A2CYP3A4CYP2D6KMT2AMAPK1 | |
| SCHEMBL17982112 | 0.66 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20565249 | 0.66 | EGFR (0.35) | CYP1A2CYP3A4CYP2D6GAAKMT2A | |
| SCHEMBL26004930 | 0.66 | NPC1 (0.37) | CYP1A2CYP3A4CYP2D6GAAKMT2A | |
| SCHEMBL4470267 | 0.65 | MEN1 (0.39) | CYP1A2CYP3A4CYP2D6KMT2ASMN1; SMN2 | |
| SCHEMBL15053249 | 0.63 | SMN1; SMN2 (0.37) | GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |