Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663307 | 0.83 | PARP1 (0.44) | PARP1HSP90AB1PDE10AACHEBCHE | |
| SCHEMBL3971551 | 0.83 | ELANE (0.41) | PARP1ACHEBCHE | |
| SCHEMBL31663247 | 0.81 | PARP1 (0.45) | PARP1ACHEBCHE | |
| SCHEMBL3107616 | 0.81 | KMT2A (0.39) | PARP1HSP90AB1PDE10AACHEBCHE | |
| SCHEMBL22215515 | 0.80 | NPC1 (0.38) | — | |
| SCHEMBL14842795 | 0.77 | PARP1 (0.47) | PARP1HSP90AB1PDE10AACHEBCHE | |
| SCHEMBL12501306 | 0.77 | PARP1 (0.50) | PARP1HSP90AB1PDE10AACHEBCHE | |
| SCHEMBL21325635 | 0.74 | ALDH1A1 (0.52) | PARP1HSP90AB1ACHEKCNH2 | |
| SCHEMBL12501303 | 0.74 | PARP1 (0.47) | PARP1HSP90AB1PDE10AACHEBCHE | |
| SCHEMBL31663149 | 0.73 | PDE10A (0.38) | PARP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |