Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5064874 | 0.91 | CYP2D6 (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4139636 | 0.89 | PPM1D (0.32) | — | |
| SCHEMBL15776868 | 0.84 | CYP2C19 (0.43) | — | |
| SCHEMBL28383552 | 0.81 | CYP2D6 (0.34) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27782501 | 0.78 | OPRM1 (0.35) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL2473117 | 0.77 | OPRM1 (0.36) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL25568329 | 0.76 | PPM1D (0.34) | — | |
| SCHEMBL30819825 | 0.74 | — | — | |
| SCHEMBL21628327 | 0.72 | PPM1D (0.31) | — | |
| SCHEMBL27942405 | 0.71 | OPRM1 (0.31) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | disclosed |