SCHEMBL31663378

SCHEMBL31663378

CC1(C(=O)O)CCN(C(=O)O)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31663382 0.83
SCHEMBL31663363 0.82 PPM1D (0.32) PPM1D
SCHEMBL28978457 0.79 PPM1D (0.43) PPM1D
SCHEMBL31663401 0.78
SCHEMBL29882268 0.77 RORC (0.39) PPM1D
SCHEMBL31663299 0.76
SCHEMBL21954152 0.72 PPM1D (0.34) PPM1D
SCHEMBL2873724 0.72 PPM1D (0.34) PPM1D
SCHEMBL2878174 0.72 PPM1D (0.34) PPM1D
SCHEMBL13740513 0.71 PPM1D (0.32) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149628-A1 PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE ASTRAZENECA AB (SE) 2025-07-17 WO disclosed