Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175520 | 1.00 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3179867 | 1.00 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3166657 | 1.00 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3160373 | 0.93 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3166362 | 0.93 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3169722 | 0.93 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL3166467 | 0.93 | HTR2A (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL17750791 | 0.84 | CYP2D6 (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL22454446 | 0.84 | CYP2D6 (0.40) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 | |
| SCHEMBL755809 | 0.83 | KCNH2 (0.46) | HTR2AKCNH2OPRM1OPRD1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888506-B1 | SEPARATION OF STEREOISOMERIC N,N-DIALKYLAMINO-2-ALKYL-3-PHENYL ALKANES | GRUENENTHAL GMBH (DE) | 2013-03-20 | — | — | EP | claimed |
| US-20080269524-A1 | Separation of Stereoisomeric N,N-Dialkylamino-2Alkyl-3-Hydroxy-3-Phenylalkanes | GRUENENTHAL GMBH (DE) | 2008-10-30 | — | — | US | claimed |
| US-7649114-B2 | Separation of stereoisomeric N,N-dialkylamino-2alkyl-3-hydroxy-3-phenylalkanes | GRUENENTHAL GMBH (DE) | 2010-01-19 | — | — | US | disclosed |
| US-20080269524-A1 | Separation of Stereoisomeric N,N-Dialkylamino-2Alkyl-3-Hydroxy-3-Phenylalkanes | GRUENENTHAL GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269524-A1 | Separation of Stereoisomeric N,N-Dialkylamino-2Alkyl-3-Hydroxy-3-Phenylalkanes | IPO8, IPO7, IPO9 | HTR2A 1865/4885KCNH2 68/4885OPRM1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.