Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17750791 | 1.00 | CYP2D6 (0.40) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL14987836 | 0.86 | KCNH2 (0.41) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL14984858 | 0.85 | KCNH2 (0.38) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL669655 | 0.85 | KCNH2 (0.38) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL14516176 | 0.85 | KCNH2 (0.46) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL755809 | 0.85 | KCNH2 (0.46) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL14974361 | 0.85 | KCNH2 (0.38) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL669373 | 0.85 | KCNH2 (0.38) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL3160373 | 0.84 | HTR2A (0.40) | CYP2D6HTR2AKCNH2OPRM1OPRD1 | |
| SCHEMBL3166369 | 0.84 | HTR2A (0.40) | CYP2D6HTR2AKCNH2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299225-A1 | PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | GRUNENTHAL GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299225-A1 | PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL | COMT, CYP1A1, CYP2E1 | CYP2D6 66/4885HTR2A 749/4885KCNH2 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.