Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394365 | 1.00 | CYP17A1 (0.39) | CYP17A1CYP19A1CYP11B1CYP11B2PDE10A | |
| SCHEMBL20406546 | 0.98 | CYP19A1 (0.41) | CYP17A1CYP19A1CYP11B1CYP11B2PDE10A | |
| SCHEMBL18661533 | 0.91 | PDE10A (0.43) | PDE10ADRD2DRD1DRD4DRD5 | |
| SCHEMBL20394220 | 0.88 | NPC1 (0.44) | CYP19A1CYP11B1CYP11B2PDE10ADRD2 | |
| SCHEMBL20394487 | 0.84 | PDE10A (0.50) | CYP19A1CYP11B1CYP11B2PDE10ADRD2 | |
| SCHEMBL20394354 | 0.82 | PDE10A (0.50) | CYP19A1CYP11B1CYP11B2PDE10AHRH3 | |
| SCHEMBL20394215 | 0.81 | PDE10A (0.46) | PDE10ADRD2DRD1DRD4DRD5 | |
| SCHEMBL20394219 | 0.81 | DRD1 (0.40) | PDE10ADRD2DRD1DRD4DRD5 | |
| SCHEMBL31663908 | 0.80 | PDE10A (0.39) | CYP19A1CYP11B1CYP11B2PDE10ASCN9A | |
| SCHEMBL20394418 | 0.80 | PDE10A (0.39) | CYP19A1CYP11B1CYP11B2PDE10ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |