Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394418 | 1.00 | PDE10A (0.39) | PDE10ASCN9AHRH4BTKCCNA2 | |
| SCHEMBL18661460 | 0.91 | PDE10A (0.42) | PDE10ACCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20394270 | 0.90 | PDE10A (0.41) | PDE10ACCNA2CDK2CDK5CDK5R1 | |
| SCHEMBL20406162 | 0.88 | PDE10A (0.42) | PDE10ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18661533 | 0.86 | PDE10A (0.43) | PDE10A | |
| SCHEMBL20406214 | 0.83 | NPC1 (0.40) | CCNA2CDK2CDK5CDK5R1CYP11B1 | |
| SCHEMBL20394220 | 0.83 | NPC1 (0.44) | PDE10ASCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL20394524 | 0.81 | PDE10A (0.36) | PDE10ACDK2 | |
| SCHEMBL31663907 | 0.80 | CYP17A1 (0.39) | PDE10ASCN9ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL20394365 | 0.80 | CYP17A1 (0.39) | PDE10ASCN9ACYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |