Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 8/20 | 0.42 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057673 | 1.00 | ATR (0.44) | ATRLCKCISD2CYP2C9CYP2C19 | |
| SCHEMBL12931843 | 0.89 | SMN1; SMN2 (0.45) | ATRLCKCISD2CYP2C9CYP2C19 | |
| SCHEMBL1058517 | 0.89 | ALDH1A1 (0.44) | ATRLCKSTK17BSTK17ABRD9 | |
| SCHEMBL10329956 | 0.84 | KMT2A (0.34) | ATRLCK | |
| SCHEMBL30862993 | 0.83 | MEN1 (0.36) | ATRLCKCISD2CYP2C9CYP2C19 | |
| SCHEMBL30050497 | 0.81 | ATR (0.37) | ATRLCKCISD2NPSR1BRD9 | |
| SCHEMBL29023131 | 0.81 | ATR (0.37) | ATRLCKCISD2NPSR1BRD9 | |
| SCHEMBL27141821 | 0.81 | ATR (0.42) | ATRLCKSTK17BSTK17ABRD9 | |
| SCHEMBL15831474 | 0.81 | ATR (0.42) | ATRLCKSTK17BSTK17ABRD9 | |
| SCHEMBL11304839 | 0.81 | ALDH1A1 (0.38) | ATRLCKSTK17BSTK17ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |