Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 7/20 | 0.59 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.59 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.47 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.45 |
| ▸ | WIZ | O95785 | 1/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070062 | 1.00 | CRBN (0.59) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL21069401 | 0.95 | CRBN (0.56) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL21069987 | 0.93 | CRBN (0.66) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL21069233 | 0.91 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL31268307 | 0.91 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL29368466 | 0.89 | CRBN (0.60) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL26147411 | 0.88 | CRBN (0.61) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL22906959 | 0.87 | CRBN (0.56) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL30399913 | 0.87 | CRBN (0.57) | CRBNDDB1GSPT1IKZF3CYP2C19 | |
| SCHEMBL31389719 | 0.87 | CRBN (0.57) | CRBNDDB1GSPT1IKZF3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |