Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.46 |
| ▸ | ROS1 | P08922 | 2/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 14/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071950 | 0.92 | ALK (0.47) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL31664109 | 0.91 | ALK (0.48) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL21069298 | 0.91 | ALK (0.48) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL21070436 | 0.91 | ALK (0.46) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL21070592 | 0.88 | ALK (0.48) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL31664188 | 0.87 | ALK (0.50) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL21070683 | 0.87 | ALK (0.50) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL1708476 | 0.86 | ALK (0.49) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL1706869 | 0.86 | ALK (0.52) | ALKROS1MAPK3EGFRMET | |
| SCHEMBL24764808 | 0.85 | ALK (0.52) | ALKROS1MAPK3EGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613773-A2 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| EP-3731869-B1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2025-07-23 | — | — | EP | disclosed |