Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.38 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.38 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20209215 | 1.00 | DRD5 (0.38) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| Formic Acid SCHEMBL21460840 | 0.96 | DRD5 (0.35) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL31666053 | 0.90 | CD38 (0.39) | HTTKDM4EMEN1KMT2ATP53 | |
| SCHEMBL21460659 | 0.90 | CD38 (0.39) | HTTKDM4EMEN1KMT2ATP53 | |
| SCHEMBL20209000 | 0.88 | HRH3 (0.44) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL21460594 | 0.88 | DRD5 (0.40) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| Hydrochloric Acid SCHEMBL21460626 | 0.87 | DRD5 (0.42) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| Formic Acid SCHEMBL21460761 | 0.86 | CD38 (0.36) | TP53MAPTPOLBCYP1A2CD38 | |
| SCHEMBL21460685 | 0.86 | DRD5 (0.40) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL21460611 | 0.85 | DRD5 (0.39) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12371436-B2 | Substituted benzodiazoliums as ENaC inhibitors | Enterprise Therapeutics Limited (GB) | 2025-07-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371436-B2 | Substituted benzodiazoliums as ENaC inhibitors | NHERF1, SCNN1B, SCNN1A | DRD5 3780/4885SCNN1A 3/4885SCNN1B 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.