SCHEMBL31666680

SCHEMBL31666680

O=c1[nH]cc(-c2nc(N[C@H]3CCCNC3)ncc2C(F)(F)F)c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CCNK O75909 20/20 0.81
▸ CDK12 Q9NYV4 20/20 0.81
▸ CCNT1 O60563 19/20 0.81
▸ CDK9 P50750 19/20 0.81
▸ CCNE1 P24864 17/20 0.81
▸ CDK2 P24941 17/20 0.81
▸ CDK7 P50613 5/20 0.81
▸ CCNH P51946 5/20 0.81
▸ MNAT1 P51948 3/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31666555 1.00 CCNK (0.81) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL24839343 0.90 CCNK (1.00) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL29498427 0.90 CCNK (1.00) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL29283738 0.87 CCNT1 (0.78) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL29749340 0.87 CCNT1 (0.78) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL29283736 0.87 CCNT1 (0.78) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL30260874 0.87 CCNK (0.94) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL31666762 0.87 CCNT1 (0.76) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL31666586 0.87 CCNT1 (0.76) CCNKCDK12CCNT1CDK9CCNE1
SCHEMBL24840734 0.85 CCNT1 (1.00) CCNKCDK12CCNT1CDK9CCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137698-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS JOINT STOCK CO «BIOCAD» (RU) 2026-05-21 — — US claimed
EP-4592283-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS Joint Stock Company "Biocad" (RU) 2025-07-30 — — EP claimed
EP-4592283-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS Joint Stock Company "Biocad" (RU) 2025-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137698-A1 CYCLIN-DEPENDENT KINASE 7 INHIBITORS CDK7, CDK6, CDK3 CCNK 13/4885CDK12 63/4885CCNT1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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