Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 4/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27143091 | 0.88 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2RORC | |
| SCHEMBL27137115 | 0.88 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2RORC | |
| SCHEMBL31603730 | 0.88 | RORC (0.37) | ESR2USP2SMN1; SMN2NR1H2RORC | |
| SCHEMBL29614642 | 0.84 | NR1H2 (0.41) | ESR2USP2SMN1; SMN2NR1H2RORC | |
| SCHEMBL29614722 | 0.84 | NR1H2 (0.41) | ESR2USP2SMN1; SMN2NR1H2RORC | |
| SCHEMBL31406695 | 0.82 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2EPHX2 | |
| SCHEMBL5251610 | 0.82 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2EPHX2 | |
| SCHEMBL654686 | 0.82 | USP2 (0.39) | ESR2USP2SMN1; SMN2NR1H2EPHX2 | |
| SCHEMBL31565399 | 0.81 | ESR2 (0.40) | ESR2USP2SMN1; SMN2NR1H2ALDH1A1 | |
| SCHEMBL27143468 | 0.81 | EPHX2 (0.39) | ESR2USP2SMN1; SMN2NR1H2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596551-A1 | COMPOUNDS WITH ANTI-KRAS MUTANT TUMOR ACTIVITY | Trasveda Ltd. (KY) | 2025-08-06 | — | — | EP | disclosed |