Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL731111 | 0.82 | — | — | |
| Ethylene SCHEMBL7065772 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3679649 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL7186057 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL3681482 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL3681484 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL4353611 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8025865 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL812158 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9009995 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8092877-B2 | includes at least 10 mole percent cycloolefin monomer residue; especially an ethylene-norbornene copolymer blended with an acyclic polyolefin such as polyethylene; resealable containers | TOPAS ADVANCED POLYMERS, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7288316-B2 | Specified glass transition temperature range, heat sealable at low temperatures; ethylene-norbornene copolymer for example; food packaging | TOPAS ADVANCED POLYMERS, INC. (US) | 2007-10-30 | — | — | US | disclosed |
| EP-1687355-A1 | CYCLOOLEFIN COPOLYMER HEAT SEALABLE FILMS | Ticona LLC (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005056634-A1 | CYCLOOLEFIN COPOLYMER HEAT SEALABLE FILMS | TICONA LLC (US) | 2005-06-23 | — | — | WO | disclosed |
| US-20050112337-A1 | Cycloolefin copolymer heat sealable films | TOPAS ADVANCED POLYMERS, INC. | 2005-05-26 | — | — | US | disclosed |
| WO-2004094493-A1 | THERMOPLASTIC AROMA BARRIER INCORPORATING CYCLO-OLEFINS | TICONA LLC (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040197505-A1 | Thermoplastic aroma barrier incorporating cyclo-olefins | REYNOLDS CONSUMER PRODUCTS INC. | 2004-10-07 | — | — | US | disclosed |
| US-6008298-A | BLENDS OF CYCLOOLEFIN COPOLYMERS WITH CORE/SHELL PARTICLES HAVING DIAMETER OF 0.01 TO 0.7 MICROMETERS; IMPROVED ELONGATION AT BREAK, FLEXURAL STRENGTH AND IMPACT STRENGTH | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-28 | — | — | US | disclosed |
| US-5863986-A | ETHYLENE WITH NORBORNENE OR TETRACYCLODODECENE IN A BLEND FOR CORE SHELL POLYMERS | TICONA GMBH (DE) | 1999-01-26 | — | — | US | disclosed |