Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 12/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16117839 | 1.00 | KRAS (0.72) | KRASERBB2FGFR1FGFR4EGLN1 | |
| SCHEMBL31672331 | 0.93 | KRAS (0.83) | KRAS | |
| SCHEMBL16100289 | 0.93 | KRAS (0.83) | KRAS | |
| SCHEMBL16117744 | 0.91 | KRAS (0.86) | KRASERBB2EGLN1SHMT2SCD | |
| SCHEMBL31672361 | 0.90 | KRAS (0.74) | KRASERBB2EGLN1SHMT2 | |
| SCHEMBL16117835 | 0.90 | KRAS (0.74) | KRASERBB2EGLN1SHMT2 | |
| SCHEMBL16102399 | 0.90 | KRAS (0.83) | KRASERBB2SHMT2 | |
| SCHEMBL16122678 | 0.89 | KRAS (0.57) | KRASERBB2FGFR1FGFR4FGFR2 | |
| SCHEMBL20240049 | 0.88 | KRAS (0.74) | KRASERBB2SHMT2SCD | |
| SCHEMBL30642292 | 0.88 | KRAS (0.76) | KRASERBB2EGLN1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |