Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDK14 | O94921 | 2/20 | 0.39 |
| ▸ | CCNY | Q8ND76 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | TXK | P42681 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 2/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608793 | 1.00 | MAPT (0.41) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL17608791 | 1.00 | MAPT (0.41) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL17800784 | 0.87 | BTK (0.40) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL17800783 | 0.87 | BTK (0.40) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL31672378 | 0.87 | BTK (0.40) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL31672384 | 0.83 | RAB9A (0.44) | RAB9ABTKKMT2AGAAKRAS | |
| SCHEMBL17608599 | 0.83 | RAB9A (0.44) | RAB9ABTKKMT2AGAAKRAS | |
| SCHEMBL16100491 | 0.83 | MAPT (0.42) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL16100490 | 0.83 | MAPT (0.42) | MAPTL3MBTL1CDK14CCNYRAB9A | |
| SCHEMBL16102029 | 0.78 | TXK (0.48) | MAPTL3MBTL1RAB9ABTKTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |