Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 0.85 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16117858 | 1.00 | KRAS (0.85) | KRASERBB2 | |
| SCHEMBL16117835 | 0.93 | KRAS (0.74) | KRASERBB2 | |
| SCHEMBL31672361 | 0.93 | KRAS (0.74) | KRASERBB2 | |
| SCHEMBL16103039 | 0.92 | KRAS (1.00) | KRAS | |
| SCHEMBL31672334 | 0.92 | KRAS (1.00) | KRAS | |
| SCHEMBL16122818 | 0.90 | KRAS (0.75) | KRAS | |
| SCHEMBL16117834 | 0.89 | KRAS (0.74) | KRASERBB2 | |
| SCHEMBL20240049 | 0.89 | KRAS (0.74) | KRASERBB2 | |
| SCHEMBL31672331 | 0.89 | KRAS (0.83) | KRAS | |
| SCHEMBL16100289 | 0.89 | KRAS (0.83) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |