Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16103039 | 1.00 | KRAS (1.00) | KRASOPRK1EGLN1 | |
| SCHEMBL16117714 | 0.96 | KRAS (0.92) | KRASOPRK1 | |
| SCHEMBL16117744 | 0.93 | KRAS (0.86) | KRASOPRK1EGLN1 | |
| SCHEMBL31672380 | 0.92 | KRAS (0.85) | KRAS | |
| SCHEMBL16117854 | 0.92 | KRAS (0.85) | KRAS | |
| SCHEMBL16117841 | 0.92 | KRAS (0.85) | KRAS | |
| SCHEMBL31672370 | 0.92 | KRAS (0.85) | KRAS | |
| SCHEMBL16117858 | 0.92 | KRAS (0.85) | KRAS | |
| SCHEMBL16117843 | 0.92 | KRAS (0.85) | KRASEGLN1 | |
| SCHEMBL31672385 | 0.91 | KRAS (0.84) | KRASOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |