Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800762 | 1.00 | RAB9A (0.45) | RAB9AKMT2AHSP90AA1HSP90AB1LMNA | |
| SCHEMBL31672338 | 0.90 | RAB9A (0.45) | RAB9AKMT2AHSP90AA1LMNATP53 | |
| SCHEMBL17800759 | 0.90 | RAB9A (0.45) | RAB9AKMT2AHSP90AA1LMNATP53 | |
| SCHEMBL16117911 | 0.83 | HSP90AA1 (0.51) | RAB9AHSP90AA1KRASACHERXFP1 | |
| SCHEMBL16101856 | 0.83 | HSP90AA1 (0.48) | RAB9AHSP90AA1LMNATP53ALOX15 | |
| SCHEMBL31672384 | 0.82 | RAB9A (0.44) | RAB9AKMT2AHSP90AA1LMNATP53 | |
| SCHEMBL17608599 | 0.82 | RAB9A (0.44) | RAB9AKMT2AHSP90AA1LMNATP53 | |
| SCHEMBL16117901 | 0.80 | HSP90AA1 (0.44) | RAB9AHSP90AA1KRASACHE | |
| SCHEMBL31672343 | 0.80 | RAB9A (0.44) | RAB9AKMT2AHSP90AA1LMNAKRAS | |
| SCHEMBL17800761 | 0.80 | RAB9A (0.44) | RAB9AKMT2AHSP90AA1LMNAKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50527-E1 | Covalent inhibitors of KRAS G12C | ARAXES PHARMA LLC (US) | 2025-08-12 | — | — | US | disclosed |