Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213770 | 0.84 | MPI (0.58) | LPAR5SGPL1MPI | |
| SCHEMBL1353551 | 0.84 | MPI (0.58) | LPAR5SGPL1MPI | |
| SCHEMBL3507132 | 0.84 | MPI (0.58) | LPAR5SGPL1MPI | |
| SCHEMBL20553435 | 0.84 | MPI (0.58) | LPAR5SGPL1MPI | |
| 1-Hexanol SCHEMBL29204266 | 0.78 | PGD (0.54) | LPAR5SGPL1PTPN1LPAR1LPAR3 | |
| SCHEMBL4594608 | 0.77 | MPI (0.62) | LPAR5SGPL1MPI | |
| SCHEMBL20857032 | 0.77 | MPI (0.62) | LPAR5SGPL1MPI | |
| SCHEMBL139868 | 0.77 | MPI (0.62) | LPAR5SGPL1MPI | |
| 1-Pentanol SCHEMBL29204291 | 0.77 | PGD (0.55) | LPAR5SGPL1PTPN1LPAR1LPAR3 | |
| Acetaldehyde SCHEMBL22264056 | 0.76 | MPI (0.56) | LPAR5SGPL1MPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641920-B1 | GLUTAMINE:FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE (GFAT) COMPRISING AN INTERNAL PURIFICATION MARKER AND USE THEREOF FOR THE SCREENING OF COMPOUNDS | CENTRE NAT RECH SCIENT (FR) | 2010-03-17 | — | — | EP | disclosed |
| EP-1641920-A1 | GLUTAMINE:FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE (GFAT) COMPRISING AN INTERNAL PURIFICATION MARKER AND USE THEREOF FOR THE SCREENING OF COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005005628-A1 | GLUTAMINE:FRUCTOSE-6-PHOSPHATE AMIDOTRANSFERASE (GFAT) COMPRISING AN INTERNAL PURIFICATION MARKER AND USE THEREOF FOR THE SCREENING OF COMPOUNDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2005-01-20 | — | — | WO | disclosed |