Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31673842 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31673829 | 0.88 | MEN1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31459976 | 0.78 | MAPT (0.75) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16312402 | 0.76 | MAPT (0.57) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16312400 | 0.76 | MAPT (0.54) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL15172955 | 0.73 | KMT2A (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31459864 | 0.73 | KMT2A (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL16521105 | 0.73 | MAPT (0.78) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL2921771 | 0.73 | MAPT (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31459968 | 0.73 | MAPT (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250255847-A1 | SIMMPYRAs: Novel Drugs for Triple Negative Breast Cancer | SIMMARON RSEARCH INC | 2025-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250255847-A1 | SIMMPYRAs: Novel Drugs for Triple Negative Breast Cancer | STAT3, STAT6, STAT1 | MEN1 4368/4885KMT2A 260/4885MAPT 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.