Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15172955 | 1.00 | KMT2A (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31459976 | 0.86 | MAPT (0.75) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3990785 | 0.82 | KMT2A (0.69) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2921771 | 0.81 | MAPT (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31459968 | 0.81 | MAPT (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31460309 | 0.80 | MAPT (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15184993 | 0.80 | KMT2A (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16521105 | 0.78 | MAPT (0.78) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4298608 | 0.76 | KDM4E (1.00) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL31673829 | 0.76 | MEN1 (0.61) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154163-A1 | Pyrimidinone-Containing 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2025-05-15 | — | — | US | disclosed |
| WO-2025090868-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154163-A1 | Pyrimidinone-Containing 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors | HSD17B13, HSD17B1, HSD11B1 | KMT2A 3204/4885MAPT 3628/4885MEN1 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.