Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.59 |
| ▸ | PPARD | Q03181 | 13/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 16/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414880 | 1.00 | PPARG (0.59) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL3003128 | 0.83 | PPARG (0.60) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL9979637 | 0.83 | PPARG (0.60) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL204645 | 0.83 | PPARG (0.60) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL13311839 | 0.83 | FFAR1 (0.46) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL8581165 | 0.82 | MAOB (0.43) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL15292428 | 0.82 | FFAR1 (0.69) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL15299338 | 0.82 | FFAR1 (0.69) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL31674239 | 0.82 | PPARD (0.59) | PPARGPPARDFFAR1PPARA | |
| SCHEMBL16188898 | 0.81 | PPARG (0.57) | PPARGPPARDFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172351-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | GPR119, INSR, GLP1R | PPARG 155/4885PPARD 133/4885FFAR1 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.