Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27123897 | 0.98 | GPR119 (0.43) | MEN1KMT2ACRBNGPR119DRD2 | |
| SCHEMBL31024371 | 0.98 | GPR119 (0.43) | MEN1KMT2ACRBNGPR119DRD2 | |
| SCHEMBL29892557 | 0.94 | GPR119 (0.43) | MEN1KMT2ACRBNGPR119PDK1 | |
| SCHEMBL27137616 | 0.92 | CRBN (0.39) | MEN1KMT2ACRBNGPR119PDK1 | |
| SCHEMBL23123648 | 0.92 | CNR1 (0.43) | MEN1KMT2ACRBNGPR119DRD2 | |
| SCHEMBL31161308 | 0.92 | CNR1 (0.43) | MEN1KMT2ACRBNGPR119DRD2 | |
| SCHEMBL27140667 | 0.91 | CRBN (0.39) | MEN1KMT2ACRBNDRD2PDK1 | |
| SCHEMBL29201711 | 0.89 | HTT (0.39) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL27137466 | 0.89 | GPR119 (0.41) | MEN1KMT2AGPR119PDK1PDK2 | |
| SCHEMBL31024364 | 0.89 | MEN1 (0.42) | MEN1KMT2ACRBNGPR119PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631942-A1 | PAN-KRAS DEGRADING AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-10-15 | — | — | EP | disclosed |
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |