SCHEMBL31678868

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	5/20	0.64

▸	CRHR1	P34998	1/20	0.63

▸	CRHR2	Q13324	1/20	0.63

▸	GLP1R	P43220	10/20	0.61

▸	GCGR	P47871	8/20	0.61

▸	RAMP1	O60894	1/20	0.57

▸	RAMP2	O60895	1/20	0.57

▸	RAMP3	O60896	1/20	0.57

▸	CALCRL	Q16602	1/20	0.57

▸	C5AR1	P21730	1/20	0.57

▸	GIPR	P48546	5/20	0.56

▸	NPY1R	P25929	1/20	0.56

▸	NPY2R	P49146	1/20	0.56

▸	NPY4R	P50391	1/20	0.56

▸	NPY5R	Q15761	1/20	0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31678921	0.89	MC4R (0.58)	CALCRGLP1RGCGRC5AR1
SCHEMBL29628084	0.89	CALCR (0.66)	CALCRCRHR1CRHR2GLP1R
SCHEMBL15787075	0.88	CALCR (0.64)	CALCRCRHR1CRHR2GLP1R
SCHEMBL30262073	0.88	CALCR (0.61)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL29836025	0.88	CALCR (0.66)	CALCRCRHR1CRHR2GLP1R
SCHEMBL719111	0.88	CALCR (0.66)	CALCRCRHR1CRHR2GLP1R
SCHEMBL30565137	0.87	CALCR (0.76)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL30932066	0.87	CALCR (0.77)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL30176470	0.87	CALCR (0.73)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL31182663	0.87	CALCR (0.63)	CALCRCRHR1CRHR2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20250268999-A1	Treatment and Prophylaxis of Amyloidosis	UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US)	2025-08-28	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20250268999-A1	Treatment and Prophylaxis of Amyloidosis	TTR, APP, MME	CALCR 1849/4885CRHR1 3880/4885CRHR2 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.