Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 7/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682111 | 1.00 | POLB (0.50) | POLBTDP1HDAC8ARADAMTS4 | |
| SCHEMBL31682053 | 0.94 | HDAC1 (0.44) | POLBTDP1HDAC8PSEN1PSEN2 | |
| SCHEMBL31682055 | 0.94 | HDAC1 (0.44) | POLBTDP1HDAC8PSEN1PSEN2 | |
| SCHEMBL31682026 | 0.93 | HDAC1 (0.43) | POLBTDP1HDAC8PSEN1PSEN2 | |
| SCHEMBL22029370 | 0.93 | TDP1 (0.41) | POLBTDP1HDAC8PSEN1PSEN2 | |
| SCHEMBL31682042 | 0.91 | HDAC1 (0.46) | POLBTDP1HDAC8PSEN1PSEN2 | |
| SCHEMBL31682121 | 0.88 | HDAC1 (0.50) | TDP1HDAC8PKMPSEN1PSEN2 | |
| SCHEMBL22029393 | 0.88 | HDAC1 (0.50) | TDP1HDAC8PKMPSEN1PSEN2 | |
| SCHEMBL31682017 | 0.88 | HDAC1 (0.50) | TDP1HDAC8PKMPSEN1PSEN2 | |
| SCHEMBL31682034 | 0.87 | TDP1 (0.46) | POLBTDP1HDAC8ARADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893934-B1 | INSULIN CONJUGATES | SANOFI SA (FR) | 2025-09-10 | — | — | EP | disclosed |