Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682121 | 1.00 | HDAC1 (0.50) | HDAC1FABP1CA12CA1CA2 | |
| SCHEMBL31682017 | 1.00 | HDAC1 (0.50) | HDAC1FABP1CA12CA1CA2 | |
| SCHEMBL31682042 | 0.95 | HDAC1 (0.46) | HDAC1FABP1CA12CA1CA2 | |
| SCHEMBL31682026 | 0.92 | HDAC1 (0.43) | HDAC1FABP1SMN1; SMN2LMNAPSEN1 | |
| SCHEMBL31682111 | 0.88 | POLB (0.50) | HDAC1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31681968 | 0.88 | POLB (0.50) | HDAC1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31682053 | 0.88 | HDAC1 (0.44) | HDAC1FABP1PSEN1PSEN2APH1B | |
| SCHEMBL31682055 | 0.88 | HDAC1 (0.44) | HDAC1FABP1PSEN1PSEN2APH1B | |
| SCHEMBL22029370 | 0.88 | TDP1 (0.41) | HDAC1FABP1PSEN1PSEN2APH1B | |
| SCHEMBL22029391 | 0.87 | CA12 (0.48) | HDAC1FABP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893934-B1 | INSULIN CONJUGATES | SANOFI SA (FR) | 2025-09-10 | — | — | EP | disclosed |
| US-12195510-B2 | Insulin conjugates | SANOFI (FR) | 2025-01-14 | — | — | US | disclosed |
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
| EP-3893934-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| EP-3894391-A1 | PEPTIDE BINDER | SANOFI (FR) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020120479-A1 | PEPTIDE BINDER | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| WO-2020120463-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | HDAC1 2572/4885FABP1 1930/4885CA12 453/4885 |
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | HDAC1 2572/4885FABP1 1930/4885CA12 453/4885 |
| US-12195510-B2 | Insulin conjugates | IAPP, INSR, IGF1R | HDAC1 2572/4885FABP1 1930/4885CA12 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.