SCHEMBL31684516

SCHEMBL31684516

Nc1nc2c(s1)CC(N)(c1ccc(C(F)(F)F)c(C(F)(F)F)c1)CC2

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MPL P40238 2/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31684735 0.88 ADORA1 (0.33) MAPT
SCHEMBL31684471 0.84 GRM2 (0.32) HSD17B10TSHR
SCHEMBL31684574 0.84 EPHX2 (0.37) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
SCHEMBL31684696 0.81 APOBEC3A (0.36) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
Bromide SCHEMBL31684672 0.81 KDM1A (0.39) HSD17B10LMNAPOLBGAAMAPT
SCHEMBL31684760 0.80 APOBEC3A (0.38) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
SCHEMBL31684649 0.79 LMNA (0.39) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
SCHEMBL31684683 0.79 APOBEC3A (0.39) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
SCHEMBL31684665 0.79 ADORA1 (0.40) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB
SCHEMBL31684600 0.79 ADORA1 (0.40) APOBEC3AAPOBEC3GHSD17B10LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4617263-A1 ARYL-CONTAINING AMINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Institute of Material Medica, Chinese Academy of Sciences (CN) 2025-09-17 EP disclosed