Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.72 |
| ▸ | SRC | P12931 | 2/20 | 0.72 |
| ▸ | TEC | P42680 | 1/20 | 0.72 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.72 |
| ▸ | ITK | Q08881 | 4/20 | 0.72 |
| ▸ | BRD4 | O60885 | 2/20 | 0.68 |
| ▸ | BTK | Q06187 | 4/20 | 0.68 |
| ▸ | JAK3 | P52333 | 3/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.65 |
| ▸ | BLK | P51451 | 1/20 | 0.65 |
| ▸ | BMX | P51813 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980983 | 1.00 | EGFR (0.72) | EGFRSRCTECSLKITK | |
| SCHEMBL28980992 | 0.93 | BRD4 (0.72) | EGFRSRCTECSLKITK | |
| SCHEMBL18371448 | 0.90 | BRD4 (0.78) | EGFRSRCTECSLKITK | |
| SCHEMBL28980968 | 0.90 | BTK (0.80) | EGFRSRCTECSLKBRD4 | |
| SCHEMBL31684778 | 0.90 | BTK (0.80) | EGFRSRCTECSLKBRD4 | |
| SCHEMBL31684788 | 0.90 | BRD4 (0.78) | EGFRSRCTECSLKITK | |
| SCHEMBL16391083 | 0.90 | EGFR (0.78) | EGFRSRCTECSLKITK | |
| SCHEMBL17002254 | 0.89 | EGFR (0.85) | EGFRSRCTECSLKBRD4 | |
| SCHEMBL12518570 | 0.87 | EGFR (0.82) | EGFRTECITKBTKJAK3 | |
| SCHEMBL28980984 | 0.87 | SRC (0.82) | SRCBRD4BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | claimed |