Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.80 |
| ▸ | JAK3 | P52333 | 4/20 | 0.79 |
| ▸ | SRC | P12931 | 4/20 | 0.76 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.76 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 5/20 | 0.76 |
| ▸ | JAK2 | O60674 | 1/20 | 0.76 |
| ▸ | BLK | P51451 | 1/20 | 0.76 |
| ▸ | BMX | P51813 | 1/20 | 0.76 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.69 |
| ▸ | TEC | P42680 | 1/20 | 0.68 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 4/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.67 |
| ▸ | CCNK | O75909 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CCND3 | P30281 | 1/20 | 0.67 |
| ▸ | CDK9 | P50750 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980968 | 1.00 | BTK (0.80) | BTKJAK3SRCMAP3K7FGFR1 | |
| SCHEMBL28980965 | 0.93 | MAP3K7 (0.81) | BTKJAK3SRCMAP3K7FGFR1 | |
| SCHEMBL31684788 | 0.91 | BRD4 (0.78) | BTKJAK3SRCEGFRJAK2 | |
| SCHEMBL18371448 | 0.91 | BRD4 (0.78) | BTKJAK3SRCEGFRJAK2 | |
| SCHEMBL31684784 | 0.90 | EGFR (0.72) | BTKJAK3SRCEGFRJAK2 | |
| SCHEMBL28980983 | 0.90 | EGFR (0.72) | BTKJAK3SRCEGFRJAK2 | |
| SCHEMBL31684777 | 0.90 | MAP3K7 (0.80) | BTKJAK3SRCMAP3K7FGFR1 | |
| SCHEMBL28980982 | 0.90 | MAP3K7 (0.80) | BTKJAK3SRCMAP3K7FGFR1 | |
| SCHEMBL10127962 | 0.89 | BTK (1.00) | BTKJAK3SRCMAP3K7FGFR1 | |
| SCHEMBL31684766 | 0.89 | MAP3K7 (0.73) | BTKJAK3SRCMAP3K7FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617261-A1 | 2,4,5-TRISUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wenzhou Medical University (CN) | 2025-09-17 | — | — | EP | claimed |