SCHEMBL31685833

SCHEMBL31685833

CN(C)c1nc2c(ncn2[C@H]2C[C@H](OP(=O)(O)O)[C@@H](CO)O2)c(=O)n1C

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ P2RY1 P47900 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.42
▸ PNP P00491 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ PDE4D Q08499 1/20 0.39
▸ PDE3A Q14432 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ RXFP1 Q9HBX9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31685478 0.87 P2RY1 (0.52) P2RY1KDM4EPNPLMNATP53
SCHEMBL31685685 0.86 P2RY1 (0.45) P2RY1KDM4E
SCHEMBL31685306 0.85 P2RY1 (0.57) P2RY1KDM4E
SCHEMBL31685610 0.85 P2RY1 (0.51) P2RY1KDM4EPNPLMNATP53
SCHEMBL31685677 0.85 PNP (0.55) PNPLMNATP53HTTPDE4D
SCHEMBL31685307 0.83 P2RY1 (0.51) P2RY1
SCHEMBL31685316 0.82 NT5E (0.52) P2RY1
SCHEMBL31685625 0.82 P2RY1 (0.51) P2RY1KDM4E
SCHEMBL31685527 0.81 P2RY1 (0.52) P2RY1KDM4EPNPLMNATP53
SCHEMBL31685380 0.81 P2RY1 (0.47) P2RY1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE TEAM MEDICAL, LLC 2025-09-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289840-A1 RNA STABILIZING SUBSTANCES AND METHODS OF USE SYNCRIP, SNRPA, RNASE1 P2RY1 2249/4885KDM4E 3958/4885PNP 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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