Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19461030 | 1.00 | NPC1 (0.47) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL19461072 | 0.93 | NPC1 (0.47) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL30642417 | 0.88 | ALDH1A1 (0.42) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL31371307 | 0.88 | ALDH1A1 (0.42) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL13454395 | 0.88 | ALDH1A1 (0.42) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL13074801 | 0.88 | ALDH1A1 (0.42) | NPC1RAB9ATSHRSMN1; SMN2TP53 | |
| SCHEMBL22634016 | 0.88 | HDAC8 (0.48) | HDAC8ALDH1A1HTTPTPN1PTPN5 | |
| SCHEMBL11991059 | 0.88 | HDAC8 (0.48) | HDAC8ALDH1A1HTTPTPN1PTPN5 | |
| SCHEMBL13205032 | 0.86 | HDAC8 (0.47) | HDAC8ALDH1A1KMT2AMEN1PTPN1 | |
| SCHEMBL11991101 | 0.86 | HDAC8 (0.47) | HDAC8ALDH1A1KMT2AMEN1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421255-B2 | Luminescence device and polycyclic compound for luminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2025-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421255-B2 | Luminescence device and polycyclic compound for luminescence device | LUC7L2, BMI1, SIRT7 | NPC1 2995/4885RAB9A 1756/4885TSHR 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.