SCHEMBL31688043

SCHEMBL31688043

C[C@@H](O)[C@H](NC(=O)[C@@H](N)CCCCNC(=N)N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 11/20 0.43
NPY1R P25929 6/20 0.43
NPY2R P49146 4/20 0.43
NPY5R Q15761 4/20 0.43
DPP7 Q9UHL4 2/20 0.42
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
NOD1 Q9Y239 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
RRM1 P23921 1/20 0.37
ENPEP Q07075 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27086265 0.96 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL27086281 0.96 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL8526706 0.96 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL8526711 0.96 NPY4R (0.44) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL29695594 0.91 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL30898573 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL30716491 0.89 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RDPP7
SCHEMBL29816322 0.88 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RPDCD1LG2
SCHEMBL30423518 0.88 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5RGNAI3
SCHEMBL31074246 0.87 ENPEP (0.49) NPY4RNPY1RNPY2RNPY5RDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296959-A1 B7-H3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF CD274, CD44, CD74 NPY4R 2286/4885NPY1R 1870/4885NPY2R 2167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.